Alcohol-Induced Behavior Change in Zebrafish Models
Zebrafish are at the forefront of neurobiological research and have been gaining popularity as a viable and valid behavioral model in a variety of research applications (e.g., assessing drug induced behavioral changes). This model becomes even more attractive when considering the behavioral changes that follow exposure to compounds that are water-soluble. As such, several studies have implicated both acute and chronic ethanol exposure in the modulation of zebrafish behavior. Within this arena there appears to be a common trend across multiple studies. As with many drugs ethanol appears to influence behavior in a dose-dependent manner. In this review, we compare and contrast several studies that measure behavior as a result of alcohol exposure. Appended to this review are pilot data that report zebrafish blood alcohol concentrations as a function of acute exposure.
Reviews in the Neurosciences
Echevarria, D. J.,
Toms, C. N.,
Jouandot, D. J.
(2011). Alcohol-Induced Behavior Change in Zebrafish Models. Reviews in the Neurosciences, 22(1), 85-93.
Available at: http://aquila.usm.edu/fac_pubs/380