Effect of Cellular Mobility on Immune Response

Authors

Ras B. Pandey, University of Southern MississippiFollow
R. Mannion, Dublin City University
H.J. Ruskin, Dublin City UniversityFollow

Document Type

Article

Publication Date

8-15-2000

Department

Physics and Astronomy

School

Mathematics and Natural Sciences

Abstract

Mobility of cell types in our HIV immune response model is subject to an intrinsic mobility and an explicit directed mobility, which is governed by P_mob. We investigate how restricting the explicit mobility, while maintaining the innate mobility of a viral-infected cell, affects the model's results. We find that increasing the explicit mobility of the immune system cells leads to viral dominance for certain levels of viral mutation. We conclude that increasing immune system cellular mobility indirectly increases the virus’ inherent mobility.

Publication Title

Physica A: Statistical Mechanics and its Applications

Volume

283

Issue

3-4

First Page

447

Last Page

450

Recommended Citation

Pandey, R. B., Mannion, R., Ruskin, H. (2000). Effect of Cellular Mobility on Immune Response. Physica A: Statistical Mechanics and its Applications, 283(3-4), 447-450.
Available at: https://aquila.usm.edu/fac_pubs/4147