Title

Effect of cellular mobility on immune response

Document Type

Article

Publication Date

8-15-2000

Department

Physics and Astronomy

Abstract

Mobility of cell types in our HIV immune response model is subject to an intrinsic mobility and an explicit directed mobility, which is governed by P-mob We investigate how restricting the explicit mobility, while maintaining the innate mobility of a viral-infected cell, affects the model's results. We find that increasing the explicit mobility of the immune system cells leads to viral dominance for certain levels of viral mutation. We conclude that increasing immune system cellular mobility indirectly increases the virus' inherent mobility. (C) 2000 Elsevier Science B.V. All rights reserved.

Publication Title

PHYSICA A

Volume

283

Issue

3-4

First Page

447

Last Page

450