Regioselective Hydration of an Alkene and Analysis of the Alcohol Product by Remote Access NMR: A Classroom Demonstration
Chemistry and Biochemistry
A two-part demonstration was conducted in our first-semester organic chemistry course designed to introduce students to the formation of alcohols, regioselective reactions, and analysis of organic products by NMR analysis. This demonstration utilized the oxymercuration-demercuration sequence to prepare an alcohol from an alkene in a Markovnikov manner because the reaction is easy to execute and has a dramatic, observable color change during the transformation. The alcohol product produced was then utilized in a classroom demonstration of NMR using a remote accessible NMR spectrometer.
Journal of Chemical Education
Smith, M. E.,
Johnson, S. L.,
Masterson, D. S.
(2013). Regioselective Hydration of an Alkene and Analysis of the Alcohol Product by Remote Access NMR: A Classroom Demonstration. Journal of Chemical Education, 90(1), 99-101.
Available at: http://aquila.usm.edu/fac_pubs/7628