Title

Neutrophil in viral infections, friend or foe?

Document Type

Article

Publication Date

1-1-2013

Department

Biological Sciences

Abstract

Polymorphonuclear leukocytes or neutrophils are the first immune cells to the site of injury and microbial infection. Neutrophils are crucial players in controlling bacterial and fungal infections, and in particular secondary infections, by phagocytosis, degranulation and neutrophil extracellular traps (NETs). While neutrophils have been shown to play important roles in viral pathogenesis, there is a lack of detailed investigation. In this article, we will review recent progresses toward understanding the role of neutrophils in viral pathogenesis. (C) 2012 Elsevier B.V. All rights reserved.

Publication Title

VIRUS RESEARCH

Volume

171

Issue

1

First Page

1

Last Page

7