A Fluorescent Dipyrrinone Oxime for the Detection of Pesticides and Other Organophosphates
Chemistry and Biochemistry
An N,N-carbonyl-bridged dipyrrinone oxime has been synthesized and studied as a potential sensor for organophosphates. The molecular sensor underwent a drastic colorimetric response upon formation of the adduct. The pesticide dimethoate was found to produce the biggest spectral response, with a limit of detection equal to 4.0 ppm using UV-visible spectroscopy. Minimal fluorescence "turn on" via a PET mechanism was seen, and molecular modeling studies were used to explain the lower than expected PET response. The X-ray crystal structure of the fluorescent dipyrrinone oxime was also obtained.
Catalano, V. J.,
Cragg, P. J.,
Huggins, M. T.,
Wallace, K. J.
(2012). A Fluorescent Dipyrrinone Oxime for the Detection of Pesticides and Other Organophosphates. Organic Letters, 14(11), 2686-2689.
Available at: http://aquila.usm.edu/fac_pubs/8864