Date of Award

Spring 5-2009

Degree Type

Dissertation

Degree Name

Doctor of Philosophy (PhD)

Department

Coastal Sciences, Gulf Coast Research Laboratory

Committee Chair

Dr. Marius Brouwer

Committee Chair Department

Coastal Sciences, Gulf Coast Research Laboratory

Committee Member 2

Dr. Mark Peterson

Committee Member 2 Department

Coastal Sciences, Gulf Coast Research Laboratory

Committee Member 3

Dr. Alexander Pozhitkov

Committee Member 3 Department

Coastal Sciences, Gulf Coast Research Laboratory

Committee Member 4

Dr. Jeffery Lotz

Committee Member 4 Department

Coastal Sciences, Gulf Coast Research Laboratory

Abstract

The blue crab, calinectes sapidus (Rathbun), is a commercial and recreation valuable crustacean species which lives in a microbially rich environment. In contrast to vertebrates, invertebrates lack of large repertoire and antigenic-recognition receptors and immunological memory that define the essential characteristics of acquired immunity in mammals. In crustaceans, circulating hemocytes are essential in immunity and perform functions such as phagocytosis of non-self particles, encapsulation, and melanization of foreign materials, production of reactive oxygen species and lysis of foreign cells. Despite supporting valuable recreational and commercial fisheries and their potential as an aquaculture species, studies on the immune function in blue crabs are limited and no large-scale gene expression work has been conducted to elucidate immune effectors of the blue crab.

for the full Abstract, please download the dissertation.

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