Title

Applications of Epigenetic Methylation In Body Fluid Identification, Age Determination and Phenotyping

Document Type

Article

Publication Date

12-1-2019

School

Criminal Justice, Forensic Science, and Security

Abstract

In this paper, four different applications are presented in forensic epigenetics using bisulfite modified PCR, HRM, and pyrosequencing. The first application involves the development of a multiplex amplification capable of simultaneous analysis of 4 different body fluid/cell types- blood, saliva, sperm, and vaginal epithelia. We have also developed a method for the detection of sperm high-resolution melt analysis (HRM). Two other applications involve a determination of suspect age and a biomarker for determining smoking status.

Publication Title

Forensic Science International: Genetics Supplement Series

Issue

1

First Page

485

Last Page

487

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