Qiaowei Pan, Laboratoire de Physiologie et Génomique des Poissons (LPGP)
Romain Feron, Laboratoire de Physiologie et Génomique des Poissons (LPGP)
Elodie Jouanno, Laboratoire de Physiologie et Génomique des Poissons (LPGP)
Hugo Darras, Université de Lausanne (UNIL)
Amaury Herpin, Laboratoire de Physiologie et Génomique des Poissons (LPGP)
Ben Koop, University of Victoria
Eric Rondeau, University of Victoria
Frederick W. Goetz, NOAA Northwest Fisheries Science Center
Wesley A. Larson, Alaska Pacific University
Louis Bernatchez, Université Laval
Mike Tringali, Fish and Wildlife Research Institute, FloridaFollow
Stephen S. Curran, Auburn UniversityFollow
Eric Saillant, Gulf Coast Research LaboratoryFollow
Gael P.J. Denys, Museum National d'Histoire Naturelle
Frank A. von Hippel, Northern Arizona University
Songlin Chen, Pilot National Laboratory for Marine Science and Technology
J. Andrés López, School of Fisheries and Ocean Sciences
Hugo Verreycken, Research Institute for Nature and Forest, Brussels
Konrad Ocalewicz, Uniwersytet Gdanski
Rene Guyomard, Génétique Animale et Biologie Intégrative
Camille Eche, INRAE
Jerome Lluch, INRAE
Celine Roques, INRAE
Hongxia Hu, Beijing Fisheries Research Institute & Beijing Key Laboratory of Fishery Biotechnology
Roger Tabor, U.S. Fish and Wildlife Service
Patrick Dehaan, U.S. Fish and Wildlife Service
Krista M. Nichols, NOAA Northwest Fisheries Science Center
Laurent Journot, Université de Montpellier
Hugues Parrinello, Université de Montpellier
Christophe Klopp, INRAE
Elena A. Interesova, Tomsk State University
Vladimir Trifonov, Novosibirsk State University
Manfred Schartl, University of Wuerzburg
John Postlethwait, University of Oregon
Yann Guiguen, INRAE, LPGP, Rennes, FranceFollow

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Coastal Sciences, Gulf Coast Research Laboratory


Ocean Science and Engineering


The understanding of the evolution of variable sex determination mechanisms across taxa requires comparative studies among closely related species. Following the fate of a known master sex-determining gene, we traced the evolution of sex determination in an entire teleost order (Esociformes). We discovered that the northern pike (Esox lucius) master sex-determining gene originated from a 65 to 90 million-year-old gene duplication event and that it remained sex-linked on undifferentiated sex chromosomes for at least 56 million years in multiple species. We identified several independent species-or population-specific sex determination transitions, including a recent loss of a Y-chromosome. These findings highlight the diversity of evolutionary fates of master sex-determining genes and the importance of population demographic history in sex determination studies. We hypothesize that occasional sex reversals and genetic bottlenecks provide a non-adaptive explanation for sex determination transitions.

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