Killing Two Birds With One Stone: Phosphorylation By a Tabun Mimic and Subsequent Capture of Cyanide Using a Single Fluorescent Chemodosimeter
Chemistry and Biochemistry
Mathematics and Natural Sciences
In the presence of the tabun mimic diethylcyanophosphonate (DECP), a fluorescent bifunctional coumarin–enamine chemodosimeter is first phosphorylated and subsequently attacked by the released cyanide ions. The reaction is disclosed in both the UV-vis and fluorescence spectra and confirmed by NMR experiments. DFT calculations support that the bis-adduct as the most thermodynamically stable species. The X-ray structure of the chemodosimeter is also reported.
New Journal of Chemistry
Cragg, P. J.,
Fronczek, F. R.,
Wallace, K. J.
(2022). Killing Two Birds With One Stone: Phosphorylation By a Tabun Mimic and Subsequent Capture of Cyanide Using a Single Fluorescent Chemodosimeter. New Journal of Chemistry, 46, 21278-21286.
Available at: https://aquila.usm.edu/fac_pubs/20572