On a Discrete Approach to Cell Dynamics in Context to Immune Response Against HIV
Physics and Astronomy
Mathematics and Natural Sciences
A network model of interacting cellular elements, such as macrophages, viruses, T4 cells, and T8 cells, is introduced to study the evolution of cell population in an early HIV infection in a cell mediated response. The mean field treatment leads to two fixed points (describing <> and <>) and a limit cycle in infected states of period two. Using a cellular automata rule for the nearest neighbour interaction, the growth of the cellular population is studied as a function of their initial concentration p ; on increasing p, a crossover from an immunodeficient to an immunocompetent state occurs at a characteristic value p(c).
Journal de Physique I
Pandey, R. B.
(1991). On a Discrete Approach to Cell Dynamics in Context to Immune Response Against HIV. Journal de Physique I, 1(12), 1709-1713.
Available at: https://aquila.usm.edu/fac_pubs/7122