Patients who live with a low quality of life and suffer from chronic pain may wish to end their suffering through different means such as active euthanasia, passive euthanasia, and physician-assisted suicide. These alternatives to end one’s own life create many ethical dilemmas for health care professionals, patients, and family members. Some of these decisions are forbidden in Islamic Religion, while others are permitted. In this paper, the authors will discuss how Islam looks at these decisions. Knowing about how Islam deals with such decisions will be of great help for health care providers who take care of Muslim patients. It will also help patients and their families in making their decisions at the end of life.