Aqueous RAFT at pH Zero: Enabling Controlled Polymerization of Unprotected Acyl Hydrazide Methacrylamides

Authors

Emily A. Hoff, University of Southern Mississippi
Brooks A. Abel, University of Southern MississippiFollow
Chase Tretbar, University of Southern MississippiFollow
Charles L. McCormick, University of Southern MississippiFollow
Derek L. Patton, University of Southern MississippiFollow

Document Type

Article

Publication Date

9-14-2017

Department

Polymers and High Performance Materials

Abstract

We report aqueous RAFT polymerization at pH = 0 mediated by a novel imidazolium-containing chain transfer agent. In 1 M HCl, unprecedented controlled polymerization and chain-extension of unprotected acyl hydrazide methacrylamides is achieved enabling the synthesis of well-defined acyl hydrazide functionalized polymer scaffolds of interest for dynamic covalent and bioconjugation strategies.

Publication Title

Polymer Chemistry

Volume

8

Issue

34

First Page

4978

Last Page

4982

Recommended Citation

Hoff, E. A., Abel, B. A., Tretbar, C., McCormick, C. L., Patton, D. L. (2017). Aqueous RAFT at pH Zero: Enabling Controlled Polymerization of Unprotected Acyl Hydrazide Methacrylamides. Polymer Chemistry, 8(34), 4978-4982.
Available at: https://aquila.usm.edu/fac_pubs/15184