An Activated Coumarin-Enamine Michael Acceptor for CN^-

Authors

Aaron B. Davis, University of Southern MississippiFollow
Rachel E. Lambert, University of Southern Mississippi
Frank R. Fronczek, Louisiana State UniversityFollow
Peter J. Cragg, University of Brighton
Karl J. Wallace, University of Southern MississippiFollow

Document Type

Article

Publication Date

7-8-2014

Department

Chemistry and Biochemistry

School

Mathematics and Natural Sciences

Abstract

Two coumarin-enamine chemodosimeters have been synthesized in three steps. They have been shown to selectively detect the cyanide ion with a fluorescent response (t_1/2 = 20 s) and a limit of detection approximately 4.2 ppb in DMSO. The X-ray crystal structure of the thermodynamically stable E-(keto) enamine isomer of one compound was obtained and exhibited offset π-stacking.

Publication Title

New Journal of Chemistry

Volume

38

First Page

4678

Last Page

4683

Recommended Citation

Davis, A. B., Lambert, R. E., Fronczek, F. R., Cragg, P. J., Wallace, K. J. (2014). An Activated Coumarin-Enamine Michael Acceptor for CN^-. New Journal of Chemistry, 38, 4678-4683.
Available at: https://aquila.usm.edu/fac_pubs/15207