Efficient Esterification of Oxidized l-Glutathione and Other Small Peptides

Authors

Emily Rose Vogel, University of Southern MississippiFollow
William Jackson, University of Southern Mississippi
Douglas S. Masterson Dr., University of Southern MississippiFollow

Document Type

Article

Publication Date

6-2015

Department

Chemistry and Biochemistry

School

Mathematics and Natural Sciences

Abstract

xidized l-glutathione was esterified to the tetra methyl ester using thionyl chloride in methanol solvent. Other alcohols were tested and the reaction progress was monitored via ESI-MS. This procedure proved to be compatible with other small peptides not containing serine and cysteine residues. In contrast to previously reported methods this procedure provided convenient access to esterified peptides requiring no purification, extended reaction times, or complicated reaction setups.

Comments

Published by Molecules at 10.3390/molecules200610487.

Publication Title

Molecules

Volume

20

Issue

6

First Page

10487

Last Page

10495

Recommended Citation

Vogel, E. R., Jackson, W., Masterson, D. S. (2015). Efficient Esterification of Oxidized l-Glutathione and Other Small Peptides. Molecules, 20(6), 10487-10495.
Available at: https://aquila.usm.edu/fac_pubs/15392