Longitudinal Changes in Body Composition and Metabolic Profile Between Exercise Clinical Trials in Men With Chronic Spinal Cord Injury

Document Type

Article

Publication Date

3-17-2016

School

Kinesiology and Nutrition

Abstract

Study design: Longitudinal design.

Objectives: The study was undertaken to determine the effects of cessation of exercise interventions on body composition and metabolic profiles in men with chronic SCI.

Settings: Clinical trials within a Medical Center.

Methods: Eleven men with motor complete SCI were followed on average over a period of 2.5 years. Six men were involved in two diffrent exercise interventions (functional electrical stimulation cycling versus arm cycling ergometer), 5 days/week for 16 weeks (exercise group), and five men served as a control (control group). Anthropometrics and dual energy X-ray absorptiometry (DXA) were captured to measure changes in lean mass (LM), fat mass (FM), percentage FM before, immediately after exercise, and after a period of 2.5 years. Basal metabolic rate (BMR) and lipid panel were also measured.

Results: Thigh circumference increased by 8.5% following exercise (P=0.42) and remained 6.4% greater than baseline measurements (P=0.012). Leg LM increased by 9% following the exercise intervention (P=0.03) and decresed by 16% in the follow-up visit (P=0.02). Percentage trunk and total body FM increased by 4.5% (P=0.008) and 3.5% (P=0.019) in the follow-up visit, respectively, and whole body LM increased by 8.4% and decreased back by 5.4% following a 2.5 year period. BMR significantly decreased by 15.5% following the exercise (P=0.029) interventions.

Conclusion: Exercise training is accompanied with positive changes in body composition as well as compensatory decrease in BMR, that regressed back following 2.5 years of exercise cessation. Participation in an exercise trial in unlikely to confound the measurements of a follow-up trial.

Publication Title

Journal of Spinal Cord Medicine

Volume

39

Issue

6

First Page

699

Last Page

712

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