Applications of Epigenetic Methylation In Body Fluid Identification, Age Determination and Phenotyping
Document Type
Article
Publication Date
12-1-2019
School
Criminal Justice, Forensic Science, and Security
Abstract
In this paper, four different applications are presented in forensic epigenetics using bisulfite modified PCR, HRM, and pyrosequencing. The first application involves the development of a multiplex amplification capable of simultaneous analysis of 4 different body fluid/cell types- blood, saliva, sperm, and vaginal epithelia. We have also developed a method for the detection of sperm high-resolution melt analysis (HRM). Two other applications involve a determination of suspect age and a biomarker for determining smoking status.
Publication Title
Forensic Science International: Genetics Supplement Series
Issue
1
First Page
485
Last Page
487
Recommended Citation
McCord, B.,
Gauthier, Q.,
Alghanim, H.,
Antunes, J.,
Tejero, N. F.,
Duncan, G.,
Balamurugan, K.
(2019). Applications of Epigenetic Methylation In Body Fluid Identification, Age Determination and Phenotyping. Forensic Science International: Genetics Supplement Series(1), 485-487.
Available at: https://aquila.usm.edu/fac_pubs/16873