Document Type
Article
Publication Date
6-1-2020
School
Polymer Science and Engineering
Abstract
Being a developed and promising approach, nanotechnology has attracted a lot of attention in biomedical and pharmaceutical therapy applications. Among nanostructured materials, mesoporous silica nanoparticles (MSNs) are effectively used as nanocarriers for drug delivery systems. MSNs can be tailored-designed by different synthetic techniques. Their morphological characteristics dictate the type of application of such materials. Recently, polymer-based materials have been employed to functionalize the MSNs surface. These modified nanocarriers are loaded with the drug and can unload their “cargo” upon exposure to either endogenous or exogenous types of stimuli. In this study, different targeting concepts, including passive, active, vascular, nuclear, and multistage targeting, are discussed.
Publication Title
Emergent Materials
Volume
3
Issue
3
First Page
407
Last Page
425
Recommended Citation
Abdo, G.,
Zagho, M.,
Khalil, A.
(2020). Recent Advances In Stimuli-Responsive Drug release and targeting concepts using mesoporous silica nanoparticles. Emergent Materials, 3(3), 407-425.
Available at: https://aquila.usm.edu/fac_pubs/19106