Amphipathic Synthetic and Biological Macromolecules In Aqueous Media
Document Type
Conference Proceeding
Publication Date
8-6-1999
Department
Chemistry and Biochemistry
School
Mathematics and Natural Sciences
Abstract
Biological and synthetic amphipathic macromolecules are often capable of forming phase-separated microdomains in response to external stimuli, for example pH, ionic strength, shear stress, and temperature. In this manuscript, we discuss the aqueous solution behavior of two synthetic polymers and a biopolymer that possess microstructural features which allow reversible associations. The first synthetic series was prepared by hydrolyzing an octylamide-modified polymer of maleic anhydride [MA] and ethyl vinyl ether [EVE]. Responsiveness to pH has been studied via energy transfer utilizing photophysical probes. The second series of copolymers was synthesized by cyclocopolymerization of N,N-diallyl-N,N-dimethyl ammonium chloride [DADMAC] and 3-(N,N-diallyl-Nmethylammonio)-1-propanesulfonate [DAMAPS]. Electrolyte responsiveness of these novel sulfobetaine copolymers is discussed as a function of composition. The final amphipathic water-soluble polymer is hydrophobin, a fungal protein secreted by Schizophyllum commune. This protein is capable of self-assembly from water onto both hydrophilic and hydrophobic surfaces as demonstrated by contact angle and AFM studies.
Publication Title
Molecular Interactions and Time-Space Organization In Macromolecular Systems
First Page
125
Last Page
139
Recommended Citation
McCormick, C.,
Armentrout, R.,
Cannon, G. C.,
Martin, G.
(1999). Amphipathic Synthetic and Biological Macromolecules In Aqueous Media. Molecular Interactions and Time-Space Organization In Macromolecular Systems, 125-139.
Available at: https://aquila.usm.edu/fac_pubs/21061
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