Association Between Occupational Sitting With High Sensitivity C-Reactive Protein: The Jackson Heart Study
Document Type
Article
Publication Date
12-23-2021
Department
Kinesiology
School
Kinesiology and Nutrition
Abstract
Modifiable, behavioral risk factors like occupational sitting may contribute to inflammation, an important cardiovascular risk factor. This study evaluated the association of self-reported occupational sitting with changes in c-reactive protein (CRP) and the role of sex. We examined occupational sitting and baseline CRP levels for 2889 African American participants in the Jackson Heart Study. Four multivariable linear regression models were estimated to determine the association of occupational sitting and CRP. Analyses were conducted in 2020. The mean age was 50.8 years and 61% were female. Participants who reported occupational sitting as “often/always” had CRP levels of 4.9±6.8 mg/L, “sometimes” had levels of 4.8±8.1 mg/L, and “never/seldom” had levels of 4.3±6.8 mg/L. In the unadjusted model, “often/always” engaging in occupational sitting was significantly associated with higher levels of CRP when compared to “never/seldom” (P < .05). This differed by sex with female participants who reported “often/always” occupational sitting had CRP levels of 6.0±7.6 mg/L compared to only 5.1±6.9 mg/L for “never/seldom.” Neither the overall association nor the female-specific association remained statistically significant in the adjusted models. We found an association between occupational sitting and inflammation, measured by CRP. This association varied by sex but did not remain significant after fully adjusting for covariates.
Publication Title
American Journal of Lifestyle Medicine
Volume
19
Issue
1
First Page
99
Last Page
108
Recommended Citation
Jones, R.,
Norris, K. C.,
McCoy, S. M.,
Thorpe, R. J.,
Bruce, M. A.,
Heitman, E.,
Beech, B. M.
(2021). Association Between Occupational Sitting With High Sensitivity C-Reactive Protein: The Jackson Heart Study. American Journal of Lifestyle Medicine, 19(1), 99-108.
Available at: https://aquila.usm.edu/fac_pubs/21883
COinS
Comments
Raymond C. F. Jones et al, Association Between Occupational Sitting With High Sensitivity C-Reactive Protein: The Jackson Heart Study, American Journal of Lifestyle Medicine (19, 1) pp. 99-108. Copyright © 2021. DOI: 10.1177/15598276211059760. Users who receive access to an article through a repository are reminded that the article is protected by copyright and reuse is restricted to non-commercial and no derivative uses. Users may also download and save a local copy of an article accessed in an institutional repository for the user's personal reference. For permission to reuse an article, please follow our Process for Requesting Permission.