West Nile Virus (Flaviviridae)

Document Type

Book Chapter

Publication Date

1-1-2020

School

Biological, Environmental, and Earth Sciences

Abstract

West Nile virus (WNV), a mosquito-transmitted flavivirus, was first discovered in Africa in 1937 and gained its entry to North America in 1999. In the past 20 years, WNV has spread to all other continents except for Antarctica and the virus has been causing significant morbidity and mortality. WNV is now considered as the most important causative agent of human viral encephalitis worldwide, however, there are still no vaccines or specific treatments available for human use. This article summarizes WNV biology, transmission, epidemiology, clinical manifestations, pathogenesis, diagnosis, prevention, and treatment implications.

Publication Title

Encyclopedia of Virology Volume 1 5 Fourth Edition

Volume

2026-01-05

First Page

884

Last Page

890

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