Chiroptical Properties of Homopolymers and Block Copolymers Synthesized From the Enantiomeric Monomers N-acryloyl-L-alanine and N-acryloyl-D-alanine Using Aqueous RAFT Polymerization

Document Type

Article

Publication Date

2006

Department

Polymers and High Performance Materials

Abstract

Chiral homo- and block copolymers based on the enantiomeric monomers N-acryloyl-l-alanine (ALAL) and N-acryloyl-d-alanine (ADAL) were prepared directly in water using controlled reversible addition–fragmentation chain transfer (RAFT) polymerization. The polymerization of the chiral monomers proceeded in a controlled fashion producing the respective homopolymers, block copolymers, and a statistical copolymer with targeted molecular weights and narrow molecular weight distributions. The chiroptical activity of these biomimetic polymers and their analogous model compounds was investigated using circular dichroism (CD). P(ALAL) and P(ADAL) were shown to be optically active exhibiting mirror image CD spectra. In addition, statistical and enantiomeric block copolymers prepared at 1:1 stochiometric ratios exhibited virtually no optical activity.

Publication Title

Australian Journal of Chemistry

Volume

59

Issue

10

First Page

749

Last Page

754

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