Inhibition of Cysteine Proteinases by Carica-Papaya Cystatin Produced in Escherichia coli
Document Type
Article
Publication Date
9-11-1995
Department
Chemistry and Biochemistry
School
Mathematics and Natural Sciences
Abstract
A papaya cystatin (Cst)-encoding cDNA clone was isolated from a papaya leaf cDNA library and the active protein produced in Escherichia coli. The amino-acid sequence reveals a protein of 11262 Da with over 40% identity to other published plant Cst. Unique features of the papaya Cst include a single Cys residue, variation in the papain-binding region, and the first reported inhibition of papaya proteinase IV by a Cst.
Publication Title
Gene
Volume
162
Issue
2
First Page
221
Last Page
224
Recommended Citation
Song, I.,
Taylor, M.,
Baker, K.,
Bateman, R. C.
(1995). Inhibition of Cysteine Proteinases by Carica-Papaya Cystatin Produced in Escherichia coli. Gene, 162(2), 221-224.
Available at: https://aquila.usm.edu/fac_pubs/5955