Size-Exclusion Chromatography of High Molecular Weight Water-Soluble Polymers

Document Type

Article

Publication Date

12-5-1991

Department

Polymers and High Performance Materials

Abstract

A preparative-scale, aqueous size-exclusion chromatography system was constructed for fractionation of large molecular weight polymers. Calibration of molecular weight to elution volume was accomplished without polymer standards by using an eluent viscosity detector in series with a refractometer. The system was found to have a hydrodynamic size-separation resolution that ranged from 500 to 3500 angstrom.

Publication Title

Journal of Applied Polymer Science

Volume

43

Issue

11

First Page

1987

Last Page

1990

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