ILOOP - A Web Application for Two-Channel Microarray Interwoven Loop Design

Authors

Mehdi Pirooznia, University of Southern MississippiFollow
Ping Gong, SpecPro, Inc.Follow
Jack Y. Yang, Harvard UniversityFollow
Mary Qu Yang, National Institutes of HealthFollow
Edward J. Perkins, U.S. Army Engineer Research and Development CenterFollow
Youping Deng, University of Southern MississippiFollow

Document Type

Article

Publication Date

1-1-2007

Department

Biological Sciences

School

Biological, Environmental, and Earth Sciences

Abstract

Microarray technology is widely applied to address complex scientific questions. However, there remain fundamental issues on how to design experiments to ensure that the resulting data enables robust statistical analysis. Interwoven loop design has several advantages over other designs. However it suffers in the complexity of design. We have implemented an online web application which allows users to find optimal loop designs for two-color microarray experiments. Given a number of conditions (such as treatments or time points) and replicates, the application will find the best possible design of the experiment and output experimental parameters. It is freely available from http://mcbc.usm.edu/iloop.

Comments

Creative Commons Attribution License

Publisher's Version

Publication Title

BMC Genomics

Volume

9

Issue

S2

First Page

1

Last Page

6

Recommended Citation

Pirooznia, M., Gong, P., Yang, J. Y., Yang, M. Q., Perkins, E. J., Deng, Y. (2007). ILOOP - A Web Application for Two-Channel Microarray Interwoven Loop Design. BMC Genomics, 9(S2), 1-6.
Available at: https://aquila.usm.edu/fac_pubs/8482