Document Type

Article

Publication Date

12-12-2006

Department

Biological Sciences

School

Biological, Environmental, and Earth Sciences

Abstract

Motivation

Graphical user interface (GUI) software promotes novelty by allowing users to extend the functionality. SVM Classifier is a cross-platform graphical application that handles very large datasets well. The purpose of this study is to create a GUI application that allows SVM users to perform SVM training, classification and prediction.

Results

The GUI provides user-friendly access to state-of-the-art SVM methods embodied in the LIBSVM implementation of Support Vector Machine. We implemented the java interface using standard swing libraries.

We used a sample data from a breast cancer study for testing classification accuracy. We achieved 100% accuracy in classification among the BRCA1–BRCA2 samples with RBF kernel of SVM.

Conclusion

We have developed a java GUI application that allows SVM users to perform SVM training, classification and prediction. We have demonstrated that support vector machines can accurately classify genes into functional categories based upon expression data from DNA microarray hybridization experiments. Among the different kernel functions that we examined, the SVM that uses a radial basis kernel function provides the best performance.

The SVM Classifier is available at http://mfgn.usm.edu/ebl/svm/

Comments

Published by BMC Bioinformatics at 10.1186/1471-2105-7-S4-S25.

Publication Title

BMC Bioinformatics

Volume

7

Issue

S4

First Page

1

Last Page

7

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