Conformational and Configurational Analysis of an N,N Carbonyl Dipyrrinone-Derived Oximate and Nitrone by NMR and Quantum Chemical Calculations

Document Type

Article

Publication Date

5-1-2011

Department

Chemistry and Biochemistry

School

Mathematics and Natural Sciences

Abstract

The geometries and relative energies of new N,N carbonyl dipyrrinone‐derived oxime molecules (E/Zscis 4a and E/Zscis 4b) have been investigated. The calculated energies, molecular geometries, and 1H/13C NMR chemical shifts agree with experimental data, and the results are presented herein. The Escis conformations of 4a and 4b and the Zscis conformation of 5b were found to be the thermodynamically most stable isomers with the oxime hydrogen atom or the methyl functional group adopting an anti‐orientation with respect to the dipyrrinone group. This conformation was unambiguously supported by a number of 2D NMR experiments. Copyright © 2011 John Wiley & Sons, Ltd.

Publication Title

Magnetic Resonance in Chemistry

Volume

49

Issue

5

First Page

205

Last Page

212

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