A New and Efficient Synthetic Route for the Synthesis of 3,6-Dimethylpyrazine-2,5-Dicarboxylic Acid Hydrate: Molecular Structure and Unique Supramolecular Interactions

Document Type

Article

Publication Date

1-1-2009

Department

Chemistry and Biochemistry

School

Mathematics and Natural Sciences

Abstract

The regioselective oxidation of 2,3,5,6,-tetramethyl pyrazine by selenium dioxide and silver nitrate resulted in the production of, 3,6-dimethylpyrazine-2,5-dicarboxylic acid hydrate in high yields. Its crystal structure, which is reported for the very first time, consists of a unique infinite three-dimensional lattice of hydrogen-bonded acid and water molecules.

Publication Title

CrystEngComm

Volume

11

Issue

4

First Page

580

Last Page

582

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