Date of Award
Summer 8-2015
Degree Type
Masters Thesis
Degree Name
Master of Science (MS)
Department
Chemistry and Biochemistry
School
Mathematics and Natural Sciences
Committee Chair
Anthony J. Bell Jr.
Committee Chair Department
Chemistry and Biochemistry
Committee Member 2
Philip D. Bates
Committee Member 2 Department
Chemistry and Biochemistry
Committee Member 3
Robert C. Bateman
Abstract
The objective is to evaluate the ability of aminoacyl-tRNA synthetases (aaRS) to recognize the non-standard nucleic acid, PNA (peptide nucleic acid). PNA has immense potential in biomedical applications due to its increased thermostability and nuclease resistance over natural nucleic acids. PNA represents a superior alternative to natural nucleic acids in many biomedical applications due to its specificity, strong binding, and nuclease resistance. This study is the initial data set that indicates PNA are recognized by translation enzymes.
Copyright
2015, Crystal Cox Serrano
Recommended Citation
Serrano, Crystal Cox, "Evaluation of the Protein Recognition Properties of Peptide Nucleic Acids" (2015). Master's Theses. 137.
https://aquila.usm.edu/masters_theses/137