Date of Award
5-2024
Degree Type
Masters Thesis
Degree Name
Master of Science (MS)
School
Kinesiology and Nutrition
Committee Chair
Jon Stavres
Committee Chair School
Kinesiology and Nutrition
Committee Member 2
Austin Graybeal
Committee Member 2 School
Kinesiology and Nutrition
Committee Member 3
Riley Galloway
Committee Member 3 School
Kinesiology and Nutrition
Committee Member 4
Stephanie Smith
Committee Member 4 School
Kinesiology and Nutrition
Abstract
Metabolic syndrome (MetS) is a complex medical condition defined by the co-occurrence of multiple cardiometabolic risk factors. Despite the well-defined profile of autonomic function in individuals with MetS, autonomic function in those with an elevated risk of developing MetS remains unclear. Our study aimed to shed light on the progression of cardiometabolic disease and its impact on autonomic function. To investigate, twenty participants, ten of whom were classified as having an elevated risk of developing MetS based on identification of risk factors using NCEP ATP III criteria, completed a two-visit study protocol. In the second visit, spontaneous cardiovagal baroreflex sensitivity (cBRS) and heart rate variability (HRV) were evaluated during ten minutes of supine rest, where heart rate (HR), beat-by-beat blood pressure (BP), and breathing frequency were recorded continuously and analyzed using the sequence method (SBP change >1.0mmHg, pulse interval change >5.0ms, r>0.80, sequence length >3 beats). Metaboreflex (MMX) responses were evaluated during 8 minutes of rhythmic handgrip at 25% maximal voluntary contraction (MVC), where HR, beat-by-by BP, and tissue oxygen saturation index (TSI) were recorded continuously. The change in mean arterial pressure vs the change in TSI were plotted to produce a slope quantifying the magnitude of the response. We found that individuals with an elevated risk of developing MetS had significantly impaired cBRS(p
ORCID ID
https://orcid.org/0009-0005-1708-2836
Copyright
2024, Ta'Quoris Newsome
Recommended Citation
Newsome, Ta'Quoris, "The Assessment of Autonomic Function in Young Adults with an Elevated Risk of Metabolic Syndrome" (2024). Master's Theses. 1033.
https://aquila.usm.edu/masters_theses/1033